Haematology 2018

OS in the FL population

Kaplan-Meier plot of OS by treatment arm (FL)

1.0

G-B, n=164

B, n=171

0.8

Pts with event, n (%) Median OS (95% CI), mo HR (95% CI), p-value*

39 (23.8)

64 (37.4)

0.6

NR (NR, NR)

53.9 (40.9, NR)

0.4

Probability

0.58 (0.39, 0.86), p=0.0061

B (n=171) G-B (n=164) Censored

0.2

+

0

Median follow-up (FL): 31.2 months (vs 21.1 months in primary analysis)

6 0

Time (months) 12 18 24 30 36 42 48

54

60

66

No. of patients at risk B G-B 159 147 171 164

0 0

137 141

122 129

103 111

84 90

65 71

49 56

32 38

13 20

7 12

NR, not reached *Stratified analysis; stratification factors: prior therapies, refractory type, geographical region

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