Hematological Malignancies

Conclusions CVD after HL (literature and Dutch HL cohort) • After mediastinal RT increased riks of coronary events, valvular disease, CHF • After 40 yrs: risk of any CVD after mediastinal RT = 50% vs 26% (no mediastinal RT) • Risk remains increased ≥ 40 yrs • Younger age at RT  higher risk • Additive effects of RT and anthracyclines on CHF risk