IMRT Course 2016

The Beaumont offline adaptive RT approach

First systematic clinical adaptive RT implementation at Beaumont Hospital, Royal Oak, Michigan: since 1997!

Yan et al. 2000: An off-line strategy for constructing a patient-specific planning target volume in adaptive treatment process for prostate cancer. IJROBP 48(1) Martinez et al. 2001: Improvement in dose escalation using the process of adaptive radiotherapy combined with three- dimensional conformal or intensity-modulated beams for prostate cancer. IJROBP 50(5)

this is why it is called ‘offline’ !

planning CT

(IMRT) plan

Fx 1

Fx 5

Fx 6

Fx N

…

…

new isocentre new plan

1 cm margin around CTV

PI, CT

PI, CT

(IMRT) plan

…

estimation of systematic setup error , characterization of internal organ motion

new, adapted PTV: ‘cl-PTV’

ESTRO IMRT course 2016 Adaptive Radiotherapy London April 7th, 2016

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