IMRT Course 2016

This was all offline ART… Now: Online Adaptive Re-Planning

M. Ghilezan et al. (2004): Online image-guided intensity-modulated radiotherapy for prostate cancer: How much improvement can we expect? A theoretical assessment of clinical benefits and potential dose escalation by improving precision and accuracy of radiation therapy. IJRPBP 60(5)

Idealized assumptions to investigate a ‘gold-standard’ benchmark online ART scheme:

• daily pre-treatment imaging and online IMRT replanning

• no intrafractional or other uncertainties => no PTV-margin necessary • evaluation using deformable dose accumulation of multiple CTs of 18 patients

Fx 1

Fx 2

Fx N

CT

CT

CT

…

IMRT plan

IMRT plan

IMRT plan

no margin!

ESTRO IMRT course 2016 Adaptive Radiotherapy London April 7th, 2016

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