IMRT Course 2016

This was all offline ART… Now: Online Adaptive Re-Planning

Ghilezan et al. 2004 (IJROBP 60(5))

Fx 1

Fx 2

Fx N

CT

CT

CT

…

IMRT plan

IMRT plan

IMRT plan

no margin!

Results (in short):

• average dose escalation by 13% possible, but with large interpatient

variation (5-41%).

• 27% of the patient would have only minimal benefit (<5% dose escalation), 32% would have significant benefit (>15% dose esc.)

Note!:

• comparison relative to non adaptive standard IMRT (1 cm margin), not to offline adaptive IMRT. • no margin, intrafraction motion and all other uncertainties neglected

ESTRO IMRT course 2016 Adaptive Radiotherapy London April 7th, 2016

-33-