IMRT

RTOG 0617: Local Tumor Failure

100

Fail

Total 213 206 p=0.0319

65 81

HR=1.37 (0.99, 1.89) Standard (60 Gy) High dose (74 Gy)

75

18-Month Local Progression Rate

50

25.1% 34.3%

25

Local Progression Rate (%) 0

0

3

6

9 12 15 18

Months since Randomization

Patients at Risk Standard High dose

213 206

205 197

187 170

165 134

137 105

113 80

85 62