IMRT

RTOG 0617: Distant Failure

100

Total 213 206 p=0.1576

Fail

97 104

HR=1.15 (0.87, 1.51) Standard (60 Gy) High dose (74 Gy)

75

18-Month Failure Rate

50

42.4% 47.8%

Distant Failure Rate (%) 0 25

9 12 15 18

0

3

6

Months since Randomization

Patients at Risk Standard High dose

145 126

115 93

94 73

73 54

213 206

205 193

175 161