IMRT

Properties of Cost Functions

Purpose: to quantify our concept of quality of a dose distribution By convention: if D 1 is better than D 2 , then F(D 1 ) < F(D 2 ) : search the minimum of F . Commonly, the cost function has the form:

1

∑ = N i 1

) (

i Df

F

=

N

N D

Dose in volume element i of an organ/tumour Number of volume elements number of regret assigned to the dose D in this volume element

i

) ( Df

ESTRO IMRT course 2015 IMRT optimization: algorithms&cost functions Brussels October 5th, 2015

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