IMRT

The most Common Physical Cost Function: One-Sided Quadratic Penalties

N

1 = ∑ = = ∑ = N i N 1 N i

2

( 1 −

( )

) DD DD

F

θ

−

0

0

overdose

i

i

2

( 1 −

( ) 0

) DD DD

F

−

θ

0

underdose

i

i

The regret grows quadratically with the violation of the required/ tolerated dose

Regret

D 0

Dose

ESTRO IMRT course 2015 IMRT optimization: algorithms&cost functions Brussels October 5th, 2015

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