IMRT

(3/4)

LOGEUD

TD50

k

46.0 + 1.8

9.95 + 3.46

Rancati (2009)

LKB

m

TD50

n

46.3 + 1.8

0.16 + 0.05 0.45 + 0.028

Rancati (2009)

1,00

all volume 2/3 volume 1/3 volume

0,90

Laryngeal edema:

0,80

0,70

•Large volume effect EUD<30-35 Gy (n=0.45) • V50<27%; mean dose <44 Gy Larynx is parallel for edema

0,60

0,50

0,40

NTCP (LKB model)

0,30

0,20

0,10

0,00

20

30

40

50

60

70

80

Dose (Gy)

Rancati et al IJROBP 2009