Imaging for Physicists

Limitations of PET for staging of lung cancer

• uptake of FDG in inflamatory sites • false negative PET after chemotherapy • small lesions (< 1 cm3) may not be seen • Respiratory motion causes blurring of image in 3D PET

free-breathing

gated

Nehmeh et al. 2004; Med. Phys. 31:3179-3186