Imaging for Physicists

PET(-CT) for staging of lung cancer

• PET improves accuracy of staging – High negative predictive value of PET for mediastinal lymph nodes • Improved staging has impact on treatment strategy – Selective irradiation of mediastinum based on PET results in low rates of nodal failure • Residual FDG uptake after treatment correlates with location of high uptake pre-treatment and is associated with worse outcome

• What is the impact of PET on delineation?