Imaging for early stage breast cancer

Severe Fibrosis (α/β = 1.9 Gy)

Fact: ✓ The larger the treated volume and/or dose, the higher the theoretical probability of complication.

Probability of fibrosis

Probability of fibrosis

40%

For details see next...

10%

Dose

Dose

Note: The dose rate (mean 0.57, range 0.26-0.89 Gy/h ) had no influence on the development of fibrosis !

University Hospital Erlangen

Dose and volume effects on fibrosis after breast conservation therapy. Borger JH et al. Int J Radiat Oncol Biol Phys. ( 1994 )