Imaging for early stage breast cancer

Severe Fibrosis (α/β = 1.9 Gy)

Fact: ✓ The larger the treated volume and/or dose, the higher the probability of complication.

Probability of fibrosis Approximately extrapolation for doses 50-60 Gy

~20%

~15%

%

~ 8-10%

~ 3-4%

~ 3%

~ 2-3%

~ 2%

<1%

Dose

University Hospital Erlangen

Dose and volume effects on fibrosis after breast conservation therapy. Borger JH et al. Int J Radiat Oncol Biol Phys. ( 1994 )