In-room imaging and MR planning

Results (2)

Nodal staging agreement between imaging results & pathology findings

Modality

Kappa

95% CI

McNemar’s test

CT/TSE

0.56

0.16 - 0.96

P = 0.019

DWI

0.97

0.84 - 1.00

• Sensitivity of 89% & specificity of 97% per LN.

• DWI allows the radiation oncologist to very closely approach the true nodal target volume:

– Dose-escalation (~ PPV of 91%)?

– Organ-sparing (~ NPV of 97%)?

• Preliminary results, require confirmation in a larger group…

Dirix P. et al. Int J Radiat Oncol Biol Phys 2010.