In-room imaging and MR planning

Study

Lesion size (cm)

Mean ADC N+ (x 10 -3 mm 2 /sec)

Mean ADC N- (x 10 -3 mm 2 /sec)

p-value Threshold (x 10 -3 mm 2 /sec)

Sens (%)

Spec (%)

1.13 ± 0.43

1.56 ± 0.51

Wang et al. Radiology 2001

> 1.0

0.002 1.22

84 91

0.41 ± 0.11

0.30 ± 0.06

Sumi et al. J Neuroradiol 2003 Abdel Razek et al. Eur Radiol 2006

> 1.0

< 0.01 0.4

52 97

0.9 – 1.5 1.09 ± 0.11

1.64 ± 0.16

< 0.04 1.38

98 88

1.17 ± 0.45

0.63 ± 0.10

Sumi et al. AJR 2006

> 1.0

< 0.001 0.74

86 94

0.4 – 1.5 0.85 ± 0.27

1.19 ± 0.22

Vandecaveye et al. Radiology 2009 de Bondt et al. Neuroradiology 2009 Holzapfel et al. Eur J Radiol 2009 Perrone et al. Eur J Radiol 2011

< 0.0001 0.94

84 94

0.5 – 3.0 0.85 ± 0.19

1.2 ± 0.24

< 0.05 1.0

92 84

0.78 ± 0.09

1.24 ± 0.16

> 1.0

< 0.05 1.02

100 87

NA

0.85

1.45

< 0.01 1.03

100 93

Lambrecht M. et al. Expert Rev Anticancer Ther 2010.