Lower GI 2017

CRMI is a better predictor of Local Recurrence after Neo-adjuvant Radiotherapy • Nagtegaal & Quirke ( 2008 ) : • Literature review – prognostic significance of CRMI in

publications between 1985 – 2006 • Data available on 17,500 patients

Predictive value of CRMI for local recurrence after multi- modality treatment greater than after surgery alone: HR for LR after neo-adjuvant therapy : 6.3 ( 3.7 – 16.7 ) HR for LR after surgery : 2.0 ( 1.4 – 2.9 )