Molecular Imaging 2017

Analysis of tumor heterogeneity

Houweling A et al. Radiother Oncol 2013;106(2):250-4.

N=18 HNC patients

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• Examined with FDG PET and DW-MRI • Voxel-based correlation of ADC values and FD uptake • Comparison of ADC- and FDG-based volumes for potential RT dose escalation

SUV

High negative Spearman correlation, High mutual information

max

SUV

ADC

SUV

min

ADC

ADC

min

max