Molecular Imaging 2017

Standard Brain MRI

T2/FLAIR reflects edema and micoscopic invasion and overestimates tumoral volume

T1 gado reflects the rupture of hematomeningeal barrier and underestimates tumoral volume

Tumor with complex infiltration Histological series : tumors 2 cm around CE CTV = CE + 2cm

What is the real tumor extension ? 95% relapse within the fields : how can we define resistant regions ?