Molecular Imaging 2017

Predictive value of diffusion for relapse ?

• ADC abnormalities overlap with the eventual recurrence in 88 % of cases and the proportion of overlap is 60 % • The ADC hypointensity itself volumetrically is much smaller than the recurrence volume • Patients with a region of diffusion restriction exhibited a significantly reduced median progression free survival of 3.2 versus 8.0 months

Elson et al, J neurooncol 2015