Particle Therapy 2017

Protons „2012“ 3 decades: 100,000 pts. 2014: 13K pts. “Rare Diseases” – “established indica0ons”: Skull base; paraspinal; sarcomas; uveal melanomas; peds . 80‘s 90‘s Carbon Ions „2012“

H&N GI

GU

Lung

Breast

Lung, Liver

Prostate Cancer

Par0cle therapy:

„the clinical evidence“ therapy:

70‘s

Clinical results of Par0cle-therapy Treated pa)ents world wide: Protons~ 100‘000 Pa)ents Carbon-Ions ~ 10000 (10%) Unprecedented Era of clinical trials in par0cle

➢ single-ins*tu*on or mul*-ins*tu*onal clinical trials (NRG, PCG, COG) ➢ Phase III: Lung, Prostate, H&N ➢ Dose escala*on trials (lung) ➢ Mul*ple Phase II trials (breast, GI, re- treatment, prostate, etc.etc. ➢ ( see www.ptcog.com)