Particle Therapy 2017

Column1 Column2 Column3 Column4 Column5 Column6 Column7 Column8 Disease Site Total Randomized / P III P I/II P0 / Pilot / Reg Completed C-Ion Sarcoma (Chordoma, Chondrosarkoma, Spine, …) 17 1 13 3 4 2 Total 199 18 114 67 37 16 * Informa4on compiled by PTCOG from par4cle therapy centers and from ClinicalTrials.gov – January 2016 Clinical Trials (acQve or completed) in ParQcle Therapy: The PTCOG List Breast (PB, Lymphnodes, Hodgkins,…) 14 1 9 4 2 CNS (Skull Base, Spine, Brain, …) 25 2 17 6 1 5 Eye (Melanoma, ReQnoblastoma, Mdeg, …) 9 0 6 3 2 GI (upper GI, Esophageal, Rectum, …) 6 1 2 3 3 1 H&N Nasal Cavity, Nasopharynx, Oropharynx,…) 20 2 7 11 5 6 Lung (NSCLC) 27 1 16 10 7 Lymphoma (Hodgkin Lymphoma, …) 4 0 1 3 1 GI (Liver) 16 2 10 4 3 GI (Pancreas) 12 0 12 0 1 1 Pediatrics (CNS, RMS, Meduloblastoma, H&N, Brain, ...) 23 0 11 12 4 GU (Prostate) 24 8 9 7 4 1 GU (Bladder, Gyn) 2 0 1 1 0

Note: Data form centers in Japan largely not reported to PTCOG