Quality Management 2017

Action limits - Proposed philosophy

Step 4: Define the center of the true dose probability distribution as the lower and upper action limit , respectively.

Prescribed dose

Probability distribution for the true dose

Dose (Gy)

is set to a minimum acceptable cure rate

TL

is set to a maximum acceptable complication rate

TL

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Clinical tolerance limits

T. From JörgenOlofsson (Dose Modeling and dose verification ESTRO COURSE)