Quantitative Methods 2017

NTCP-models Levels of evidence

Level Description Level 1a External validation in separate dataset in other centre using new technology External validation in separate dataset in same centre using new technology , OR External validation in separate dataset in other centre using standard technology Level 2a External validation in separate dataset in same centre using non-random dataset Level 2b External validation in separate dataset in same centre using random split dataset Level 3 Development and internal validation Level 4a Multivariable model without any validation Level 4b Univariable model Level 1b