Quantitative Methods 2017

Rapid Learning Health Care ‘Valdation train’ approach

Intercept

0 0 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440

-2

-4

-6

-8

Regression coefficient

0 0.02 0.04 0.06 0.08 0.1 0 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 Regression coefficient Mean dose PCM superior Decision support system ‘RLHC-system validation train approach’: 1. No change 2. Recalibration intercept 3. Recalibration intercept and slope 4. Refit

Mean dose supraglottic

0.04

0.03

0.02

0.01

0

0 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 Regression coefficient

work in progress