SBRT 2016

PREDICTORS BILIARY TRACT TOXICITY

• Retrospective 96 liver patients • Median dose 40Gy in 5 fractions (25-54Gy in 1-5 fractions)

• CCA: - biliary obstruction/stricture - hepatobiliary infections

• Toxicity associated with SBRT dose-parameters • V BED 10 72Gy< 21cc V BED 10 66Gy< 24cc

Osmudson EC. Predictors of toxicity associated with SBRT to the central hepatobiliary tract. IJROBP 2014