SBRT 2016

HEPATIC TOXICITY SBRT STUDIES

• Reported CTC grade ≥ 3 hepatic: - Elevation liver enzymes - Hyperbilirubinemia/Hypoalbuminemia/Elevation INR - Child Pugh decline - Death due to decompensation

• Hepatic toxicity influences prognosis: - Greater risk of death (Lasley FD. PRO 2015) - 2 year survival (Sanuki N. Hepat Research 2015)