SBRT2015

Recurrences : not operable !!!

Chemotherapy/targeted therapies Response rate 10-35% Median survival 5-9 months CDDP, Targeted therapy (EGFr, VEGF…)

Soulieres et al JCO 2004 Vermorken et al. 2008

Reirradiation +/- CT ??? New drugs New irradiation techniques ?

3D IMRT STEREOTAXIE