Target Volume Determination 2015

Per-treatment target volume changes

Per-treatment GTV (CT) volume changes (observational studies)

Reference

Radiotherapy technique 2DRT/3DCRT

Per-treatment imaging time

Δ per-treatment volume/ pretreatment volume

Fang 2001

Week 5

GTV-T: -62% GTV-N: -76%

GTV-T: -1.7%/day GTV-N: -1.7%/day

Barker 2004

2DRT/3DCRT/IMRT

3/week

GTV sum :-36-47%

Yang 2010

IMRT

Week 4-5

GTV

GTV Week 5 CTV

Height 2010

IMRT

GTV-T: -50% GTV-N: -74%

CTV

PTV

PTV

Fang et al. IJROBP 2001;50:961-9. Barker et al. IJROBP 2004;59:960-70. Yang et al. IJROBP 2011;79:1096-103. Height et al . J Med Imaging Radiat Oncol 2010;54:497-504.