paediatrics Brussels 17

Medulloblastoma Differences between adults and children • Incidence of late relapses: in children late relapses uncommon. In adult series, similar plateaus normally not observed • Type of metastatic spread: in children majority of relapses are disseminated and in the CNS. In adults there is a higher tendency for isolated relapses, the relative contribution of extracranial metastases is higher, although still uncommon