paediatrics Brussels 17

Craniospinal RT Dose (1800 cGy)

• Children’s Hospital of Philadelphia • A prospective study used 1800 cGy CSRT and 5580 cGy to the posterior fossa with 8 cycles of VCR, CCNU and CDDP in 10 children 18-60 mos • 4-year survival was 69% • No marked change in IQ scores among survivors

Goldwein JW et al. Int J Radiat Oncol Biol Phys 1996; 34:899-904