paediatrics Brussels 17

Craniospinal RT Dose (1800 cGy)

• Indiana University • 7 children (age 20-64 mos) treated with 4 mos of chemotherapy followed by 1800 cGy CSRT + 54 Gy PF boost • 3 patients relapsed (all outside PF) • 2 of 3 were salvaged • 4/6 survivors have endocrine deficits • All 6 required special assistance in school

Jakacki RI et al. Int J Radiat Oncol Biol Phys 2004; 60:531-6