paediatrics Brussels 17

Radiation Dose – Current COG Protocol

 GTV1, CTV1, and PTV1 are defined • 45 Gy in 1.8 Gy are delivered based on pre-chemo extent  GTV2 defined as residual visible or palpable tumor by imaging or physical exam • For unresected or partially resected tumors, GTV2 includes pre-treatment abnormalities in bone and gross tumor in soft tissue post-chemo • CTV2=GTV2 + 1 cm • PTV2 = 10.8 Gy for total of 55.8 Gy

 Post-op RT: 50.4 Gy for R1 and 55.8 Gy for R2