Advanced TP

Parameters for clinical outcome: Brain

10 15 20 25 30

10 15 20 25 30

< 2.5 Gy

≥ 2.5 Gy

d 1

d 1

n<60 n=160-120 n>120

n<60 n=160-120 n>120

0 5

0 5

0 25 50 75 100 125 150 175 200

0 25 50 75 100 125 150 175 200

BED (Gy)

10 15 20 25 30 35 40 45 50

Twice daily fraction

n<60 n=160-120 n>120

Radiation necrosis (%)

Lawrence YR et al. Radiation Dose-Volume effects in the brain. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S20–S27, 2010.

0 5

0

25

50

75

100

125

150 175 200