BCRB 2018

19/09/2018

In situ assays

• In situ assays (growth delay, tumor control): • Tumors left in place • Measure response of effective and potential stem cells • Limitation: no quantification of stem cells; surviving fraction is difficult to assess

27

Tumor regression ≠ cell survival

Hermens and Barendsen, Eur. J. Cancer 1969