Basic Clinical Radiobiology 2017

Combined chemo- and radiotherapy treatment: Cellular / molecular interaction

Antibiotics

DNA damage Chromosome Cell Apoptosis induction repair aberration Cycle

Mitomycin-C Bleomycin Actinomycin-D

? ? ?

? - +?

- -/+ ?

? + ?

? ? -

ESTRO 2017

Combined chemo- and radiotherapy treatment Cellular / molecular interaction or Tissular interaction ?

ESTRO 2017