Basic Clinical Radiobiology 2017

Hypoxic tracer 18 FAZA

ESTRO 2017

18 F-AZA image segmentation Hypoxic subvolume: > mean SUV muscle + 3 SD Hypoxic subvolume in the tumor according to this definition: SUV mean muscle + 3 SD

3.5

3

2.94

2.63

2.5

2.45

2.32

2.28

2

1.92

1.77 1.77

1.77 1.67 1.

1.67

1.53 1.63

1.62

1.61 1.47

1.57 1.39

1.55

SUV SUV

1.5

1.50

1.43

1.42

1.35

1

0.98

0.75

0.74

0.72

0.67

0.63

0.56

0.52

0.5

0.49

0.48

0.4

0

1

2

3

4

5

6

7

8

9

10

11

Patient n° Patient #

ESTRO 2017

S. Servagi, 2013