CPB Ljubljana 2018 course book

Electronic skin brachytherapy – early results

Author/ year

N patients/N lesions/ histopatholo gy

Applicat or

N frac- tions

Dose fractio n

Prescri p-tion depth

Total dose (Gy)

Frequ ency

Median follow up (months ) At least 1 year

Local contro l

Acute toxicit y G ≥ 3

Comment s

Ballester – Sanchez 2016 [41]

20p BCC 20p BCC

Esteya® 6 6

6.1 7 Gy

3 - 4 mm 36.6 42

Twice a week

90% 95%

no

Very good cosmesis

Bhatnagar 2013,2015 [42,43]

297p NMSC 167p BCC

Xoft® 8

5 Gy CT

40 Twice

16.5 99

-

-

based or 3 mm

a week

Dogget 2015 [44] Strimling 2015 [45] Paravati 2015 [46]

565p NMSC 238p BCC 508p NMSC 275p BCC 154p NMSC 149p BCC

Xoft® 8

5 Gy -

40 Twice

12.5 99.8 -

-

a week

Xoft® 8

5 Gy 0-5 mm 40 Twice a week 5 Gy 2-3 mm 40 Twice a week

3.4

99.4 -

-

Xoft® 8

16

98.7 -

-

Goyal 2015 [47]

19p/23 20 BCC 3 SCC

Xoft® 8 – 20 (mean 10)

4 Gy – in 20 lesions

US Based mean 2.1 mm (1-3.4)

Mean 40 (32- 50)

Daily 12

100 no

US to decide depth and lateral extension