ESTRO 2024 - Abstract Book

S2430

Clinical - Urology

ESTRO 2024

Conclusion:

These findings based on correlated development patterns identified different time evolutions of EF and other sexual domains after radiotherapy for PCa. Evaluating the impact of radiotherapy on EF is not straightforward as several variables come into play including baseline status, partner, aging, clinical and personal factors. This analysis found clusters of patients with stable-low and stable-high EF scores, while a group with high function before treatment experienced a considerable worsening. However, despite a proportion of patients with worsening EF also reported a decline in OS, some were still satisfied with their sexual life. Interestingly, a group of patients with stable low EF scores reported a stable-high/medium OS after treatment. Focusing predictive modeling on groups of patients with worsening compared to baseline can help in identifying risk factors and dose-effects to avoid radiation-induced erectile dysfunction. However, results show that the impact on sexual health goes beyond EF, and individualized supportive care strategies could help patients in improving their overall satisfaction after treatment.

Keywords: prostate cancer, erectile function, sexual health

References:

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