ESTRO PT 2018

PTCOG GU Subcommittee Workshop Prospective Comparison of Outcomes in Prostate Cancer Patients Treated with Photons or Protons February 3-5, 2017, Amelia Island

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Outcome Comparison between prospective,

Design justified by patient engagement Avoids issues of: • equipoise • disincentives • patient selection

All prostate patients*

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controlled, non-randomized parallel cohorts of patients treated contemporaneously by the same pragmatic protocol with Protons or Photons for Prostate Cancer

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patient choice

insurance

Proton Cohort

Photon Cohort

Photon sites chosen to minimize propensity adjustments needed .