Imaging for early stage breast cancer

APBI with 3D-CRT vs. IMRT (63 patients)

3D-CRT %

IMRT %

Reduction %

CTV V95

98.4

98.2

0.2

PTV V95

96.0

88.8

8

Ipsilat. nontarget breast V50 Ipsilat. nontarget breast V100

34.5

28.1

19

5.8

0.4

93

Ipsilat. lung V20Gy

2.3

1.2

48

Heart V5Gy

1.7

0.6

65

- IMRT improves normal tissue sparing in the ipsilateral breast without compromising dose delivery to clinical target volume

- IMRT has more advantages in patients with more challenging anatomy , such as smaller

breast size, a larger PTV/breast ratio, or tumors in the vicinity of the heart

Rusthoven et al. IJROBP 70:296-302. 2008