Imaging for early stage breast cancer

APBI with helical Tomotherapy

- two plans for 10 patients (standard helical and fixed beam (topotherapy ))

- NSABP B-39/RTOG 0413 guidelines for target coverage and normal tissue dosimetry

Topotherapy beams

Helical

Topotherapy

Target

V100 (%)

95

95

Uninvolved ipsilat. breast

V50 (%)

30

40

Ipsilat. lung

V10Gy (%)

17

10

Heart (left sided)

V2Gy (%)

13

5

The conformation of the prescription dose to the target was greater for helical deliveries ,

while the ipsilateral lung and heart dose were significantly reduced for the topotherapy plans.

Langen et al. IJROBP 70:1272-80. 2008